Reconstruction of three-dimensional microvascular networks from two-photon imaging data
When
4 – 5 p.m., Oct. 17, 2023
Where
Two-photon microscopy can be used to obtain images of three-dimensional biological structures, such as networks of microvessels. Typically, this method yields a "z-stack" of two-dimensional gray-scale images. We will discuss methods for deriving network structures from such data, expressed in terms of nodes and segments with specified topology and geometry. This work has applications for studying the structure and function of the microcirculation in the brain.